1.02020-04-17 19:10:36 UTC2020-11-18 16:39:23 UTCCDB005113Phosphohydroxypyruvic acidPhosphohydroxypyruvic acid, also known as 3-phosphooxypyruvate or hydroxypyruvic acid phosphate, belongs to the class of organic compounds known as glycerone phosphates. These are organic compounds containing a glycerone moiety that carries a phosphate group at the O-1 or O-2 position. Phosphohydroxypyruvic acid is a moderately acidic compound (based on its pKa). Phosphohydroxypyruvic acid exists in all living species, ranging from bacteria to humans. Within humans, phosphohydroxypyruvic acid participates in a number of enzymatic reactions. In particular, phosphohydroxypyruvic acid can be biosynthesized from 3-phosphoglyceric acid through the action of the enzyme D-3-phosphoglycerate dehydrogenase. In addition, phosphohydroxypyruvic acid and L-glutamic acid can be converted into phosphoserine and oxoglutaric acid through its interaction with the enzyme phosphoserine aminotransferase. In humans, phosphohydroxypyruvic acid is involved in the metabolic disorder called the dimethylglycine dehydrogenase deficiency pathway. A carboxyalkyl phosphate that is pyruvic acid substituted at position 3 by a 3-phosphonooxy group. Phosphohydroxypyruvic acid is expected to be in Cannabis as all living plants are known to produce and metabolize it.3-Phosphohydroxypyruvic acidHydroxypyruvic acid phosphate3-Phosphonooxypyruvic acid3-Phosphohydroxypyruvate3-PhosphooxypyruvateHydroxypyruvate phosphateHydroxypyruvic acid phosphoric acid3-Phosphonooxypyruvate3-Phosphooxypyruvic acidPhosphohydroxypyruvate2-oxo-3-(Phosphonooxy)-propanoate2-oxo-3-(Phosphonooxy)-propanoic acid3-Phosphonatooxypyruvate2-Oxo-3-(phosphonooxy)propanoic acid2-Oxo-3-(phosphonooxy)propionic acidPhosphohydroxypyruvic acidC3H5O7P184.04183.97732-oxo-3-(phosphonooxy)propanoic acidphosphohydroxypyruvate3913-50-6OC(=O)C(=O)COP(O)(O)=OInChI=1S/C3H5O7P/c4-2(3(5)6)1-10-11(7,8)9/h1H2,(H,5,6)(H2,7,8,9)LFLUCDOSQPJJBE-UHFFFAOYSA-N belongs to the class of organic compounds known as glycerone phosphates. These are organic compounds containing a glycerone moiety that carries a phosphate group at the O-1 or O-2 position.Glycerone phosphatesOrganic compoundsOrganic oxygen compoundsOrganooxygen compoundsCarbonyl compoundsAliphatic acyclic compoundsAlpha-hydroxy ketonesAlpha-keto acids and derivativesCarboxylic acidsHydrocarbon derivativesMonoalkyl phosphatesMonocarboxylic acids and derivativesMonosaccharidesOrganic oxidesAliphatic acyclic compoundAlkyl phosphateAlpha-hydroxy ketoneAlpha-keto acidCarboxylic acidCarboxylic acid derivativeGlycerone phosphateHydrocarbon derivativeKeto acidMonoalkyl phosphateMonocarboxylic acid or derivativesMonosaccharideOrganic oxideOrganic phosphoric acid derivativePhosphoric acid estercarboxyalkyl phosphatelogp-1.75logs-1.14logp-0.87pka_strongest_acidic1.02iupac2-oxo-3-(phosphonooxy)propanoic acidaverage_mass184.04mono_mass183.9773smilesOC(=O)C(=O)COP(O)(O)=OformulaC3H5O7PinchiInChI=1S/C3H5O7P/c4-2(3(5)6)1-10-11(7,8)9/h1H2,(H,5,6)(H2,7,8,9)inchikeyLFLUCDOSQPJJBE-UHFFFAOYSA-Npolar_surface_area121.13refractivity30.56polarizability12.69rotatable_bond_count4acceptor_count6donor_count3physiological_charge-3formal_charge0number_of_rings0bioavailability1rule_of_fiveYesghose_filterYesveber_ruleYesmddr_like_ruleYesFDB022377C0323210510330933C0001965741453Phosphohydroxypyruvic acid4843-P-HYDROXYPYRUVATE