1.02020-04-17 19:07:31 UTC2020-11-18 16:39:18 UTCCDB005082Fructose 6-phosphateFructose 6-phosphate, also known as neuberg ester or D-fructose-6-p, belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. The open chain form of D-fructose 6-phosphate. Fructose 6-phosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). Fructose 6-phosphate exists in all living species, ranging from bacteria to humans. fructose 6-phosphate and L-glutamine can be converted into glucosamine 6-phosphate and L-glutamic acid through the action of the enzyme glutamine--fructose-6-phosphate aminotransferase. In humans, fructose 6-phosphate is involved in homocarnosinosis. Outside of the human body, Fructose 6-phosphate has been detected, but not quantified in, carrots and milk (cow). This could make fructose 6-phosphate a potential biomarker for the consumption of these foods. Fructose 6-phosphate is expected to be in Cannabis as all living plants are known to produce and metabolize it.D-Fructose 6-phosphateD-Fructose 6-phosphoric acidFructose-6-phosphateNeuberg esterFructose-6-phosphoric acidFructose 6-phosphoric acidD-Fructose 6-phosphorateD-Fructose-6-pD-Fructose-6-phosphateFPCFru-6-pFructose-6-pFructose-6PFructose-6-phosphate, (alpha-D)-isomerFructose-6-phosphate, (beta-D)-isomerFructose-6-phosphate, disodium salt, (D)-isomerFructose-6-phosphate, (D)-isomerFructose-6-phosphate, 1-(14)C-labeled, (D)-isomerFructose-6-phosphate, 2-(14)C-labeled, (D)-isomerFructose-6-phosphate, barium (1:1) salt, (D)-isomerFructose-6-phosphate, barium salt, (D)-isomerFructose-6-phosphate, sodium salt, (D)-isomerFructose-6-phosphate, calcium salt, (D)-isomerFructose-6-phosphate, magnesium (1:1) salt, (D)-isomerFructose-6-phosphate, sodium saltC6H13O9P260.14260.0297{[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl]oxy}phosphonic acidD-fructose 6-phosphate643-13-0OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=OInChI=1S/C6H13O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h4-7,9-11H,1-2H2,(H2,12,13,14)/t4-,5-,6-/m1/s1GSXOAOHZAIYLCY-HSUXUTPPSA-N belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups.Hexose phosphatesOrganic compoundsOrganic oxygen compoundsOrganooxygen compoundsCarbohydrates and carbohydrate conjugatesAliphatic acyclic compoundsAcyloinsAlpha-hydroxy ketonesBeta-hydroxy ketonesHydrocarbon derivativesMonoalkyl phosphatesMonosaccharide phosphatesOrganic oxidesPolyolsPrimary alcoholsSecondary alcoholsAcyloinAlcoholAliphatic acyclic compoundAlkyl phosphateAlpha-hydroxy ketoneBeta-hydroxy ketoneCarbonyl groupHexose phosphateHydrocarbon derivativeKetoneMonoalkyl phosphateMonosaccharide phosphateOrganic oxideOrganic phosphoric acid derivativePhosphoric acid esterPolyolPrimary alcoholSecondary alcoholD-fructose 6-phosphatewater_solubility911 mg/mLlogp-1.86logs-1.05logp-3.4pka_strongest_acidic1.49pka_strongest_basic-3.3iupac{[(2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl]oxy}phosphonic acidaverage_mass260.14mono_mass260.0297smilesOCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=OformulaC6H13O9PinchiInChI=1S/C6H13O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h4-7,9-11H,1-2H2,(H2,12,13,14)/t4-,5-,6-/m1/s1inchikeyGSXOAOHZAIYLCY-HSUXUTPPSA-Npolar_surface_area164.75refractivity48.43polarizability20.78rotatable_bond_count7acceptor_count8donor_count6physiological_charge-2formal_charge0number_of_rings0bioavailability1rule_of_fiveYesghose_filterYesveber_ruleYesmddr_like_ruleYesC00085DB04493FDB021896627136950715946CPD-15709Fructose 6-phosphate337955159