Showing Compound Card for Hexacosane (CDB000163)

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Record Information
Version1.0
Created at2020-03-18 23:27:07 UTC
Updated at2020-12-07 19:07:11 UTC
CannabisDB IDCDB000163
Secondary Accession NumbersNot Available
Cannabis Compound Identification
Common NameHexacosane
DescriptionHexacosane, also known as CH3-[CH2]24-CH3, is straight-chain alkane comprised of 26 carbon atoms. It belongs to the class of organic compounds known as alkanes. These are acyclic branched or unbranched hydrocarbons having the general formula CnH2n+2, and consist entirely of hydrogen atoms andsaturated carbon atoms. Hexacosane is a hydrocarbon lipid molecule that is very hydrophobic, practically insoluble in water, and relatively neutral. Hexacosane has been detected in peachs, sunflowers, parsnips, coconuts, and papaya. This could make hexacosane a potential biomarker for the consumption of these foods. Hexacosane is an abundant alkane found in cannabis plants (PMID: 6991645 ). Hexacosane, isolated from Sansevieria liberica, exhibited antimicrobial activity against Klebsiela pnemoniae, Salmonela typhi, Mithecithinne staphaureus and Proteus vulgaris (  Ref:DOI ). Hexacosane is also found in cannabis smoke and is volatilized during the combustion of cannabis ( Ref:DOI ).
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
ValueSource
CH3-[CH2]24-CH3ChEBI
N-HexacosaneChEBI
Chemical FormulaC26H54
Average Molecular Weight366.71
Monoisotopic Molecular Weight366.4226
IUPAC Namehexacosane
Traditional Namehexacosane
CAS Registry Number630-01-3
SMILES
CCCCCCCCCCCCCCCCCCCCCCCCCC
InChI Identifier
InChI=1S/C26H54/c1-3-5-7-9-11-13-15-17-19-21-23-25-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-26H2,1-2H3
InChI KeyHMSWAIKSFDFLKN-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as alkanes. These are acyclic branched or unbranched hydrocarbons having the general formula CnH2n+2 , and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.
KingdomOrganic compounds
Super ClassHydrocarbons
ClassSaturated hydrocarbons
Sub ClassAlkanes
Direct ParentAlkanes
Alternative ParentsNot Available
Substituents
  • Acyclic alkane
  • Alkane
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
Disposition

Biological location:

Role

Industrial application:

Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
logPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP10.66ALOGPS
logP12.02ChemAxon
logS-8ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count23ChemAxon
Refractivity121.43 m³·mol⁻¹ChemAxon
Polarizability54.84 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
EI-MS/GC-MS
TypeDescriptionSplash KeyView
EI-MSMass Spectrum (Electron Ionization)splash10-0abc-9210000000-e273d503bbb10291b1732015-03-01View Spectrum
GC-MSHexacosane, non-derivatized, GC-MS Spectrumsplash10-00dr-9300000000-b7628fa4588904f72511Spectrum
GC-MSHexacosane, non-derivatized, GC-MS Spectrumsplash10-0a4l-9000000000-8ff648370df9ab839d2dSpectrum
GC-MSHexacosane, non-derivatized, GC-MS Spectrumsplash10-0a4l-9000000000-e37e2b4f024d8a92f5a7Spectrum
Predicted GC-MSHexacosane, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positivesplash10-000g-9862000000-61f9268d4cd56b18c081Spectrum
Predicted GC-MSHexacosane, non-derivatized, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
MS/MS
NMR
TypeDescriptionView
1D NMR1H NMR Spectrum (1D, 400 MHz, CDCl3, experimental)Spectrum
1D NMR13C NMR Spectrum (1D, 25.16 MHz, CDCl3, experimental)Spectrum
Pathways
Pathways
Protein Targets
EnzymesNot Available
TransportersNot Available
Metal BindingsNot Available
ReceptorsNot Available
Transcriptional FactorsNot Available
Concentrations Data
Not Available
HMDB IDHMDB0061867
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FoodDB IDFDB001818
KNApSAcK IDC00030478
Chemspider ID11901
KEGG Compound IDNot Available
BioCyc IDCPD-9763
BiGG IDNot Available
Wikipedia LinkHigher alkanes
METLIN IDNot Available
PubChem Compound12407
PDB IDNot Available
ChEBI ID32940
References
General References
  1. Turner CE, Elsohly MA, Boeren EG: Constituents of Cannabis sativa L. XVII. A review of the natural constituents. J Nat Prod. 1980 Mar-Apr;43(2):169-234. doi: 10.1021/np50008a001. [PubMed:6991645 ]